What medication is associated with the iPledge program?

The medication associated with the iPledge program is isotretinoin, which is most commonly known by its brand name, Accutane. The iPledge program is a risk management system implemented by the FDA to prevent fetal exposure to isotretinoin due to its high teratogenic potential. Isotretinoin is used primarily for the treatment of severe acne that has not responded to other therapies.

This program requires patients, prescribers, and pharmacies to enroll in a database that monitors prescriptions and helps ensure the strict guidelines are followed. For example, female patients must agree to use two forms of contraception and undergo regular pregnancy tests while on the medication, highlighting the importance of adhering to safe usage protocols for this potentially harmful medication.

Brand names like Accutane are often closely recognized, but they are not the drugs themselves; rather, they represent specific formulations or manufacturers of isotretinoin. The focus on isotretinoin emphasizes the clinical significance and regulatory measures surrounding its use, particularly concerning female patients of childbearing age.

Other medications listed, such as finasteride and metformin, are not part of the iPledge program and do not have the same level of restrictions or requirements for monitoring and managing risks related to